Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
USERS' SCORE
Good
Based on 103 Reviews
8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
1,360 mcg DFE** (800 mcg folic acid)
340%
Vitamin B-12 (as Cyanocobalamin)
25 mcg
1042%

Top Medical Research Studies

8
Folic acid treatment shows promise
We explored the effects of folic acid on hair loss in a three-week-old Charolais calf showing signs typical of folic acid deficiency. After starting daily folic acid therapy at a dose of 1 mg/kg, we observed that the crusts and patches diminished within two weeks. Remarkably, hair growth resumed, and within two months, the calf returned to a normal state. This indicates that folic acid could be an effective treatment for certain types of alopecia related to deficiencies in this essential nutrient.
Read More
We explored the effectiveness of two nutritional supplements for treating telogen effluvium (TE), a common form of hair loss. Over 180 days, female participants received either a nutrient-rich supplement containing folic acid or an alternative formulation.

Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.

This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Read More
7
Folic acid shows limited protective effects
We explored the effects of folic acid on hair loss in zebrafish larvae after exposure to different concentrations of ethanol. This study revealed how gestational ethanol exposure can harm the development of sensory hair cells. We found that even small amounts of ethanol lead to a significant decrease in hair cell count.

When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.

Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
Read More

Most Useful Reviews

9
Mood improved
20 people found this helpful
After two months on these supplements, my hair loss stopped within the first month. My overall health improved, especially my mood and sleep quality. I also noticed an enhancement in my skin condition, although that may relate more to my skincare routine.
Read More
9
Overcame hair loss
14 people found this helpful
Folic acid with Biotin helped me during a crisis of hair loss. An integrated approach, perhaps including Merz vitamins, contributed to my success. Many believe only pregnant women need folic acid, but everyone, including men, does. Factors like smoking and poor diet can lead to a common deficiency. Symptoms may include irritability and hair loss. After two weeks, my psycho-emotional state improved, my skin became more even, dryness reduced, and notably, hair loss decreased considerably. My hair did become greasier at the roots, and the scalp was less dry throughout the supplementation period.
Read More
9
Recommended by doctor
6 people found this helpful
My doctor suggested this before pregnancy for fetal health, and I noticed it significantly helped my hair loss. I highly recommend it.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
  • All Researches
We explored the effectiveness of two nutritional supplements for treating telogen effluvium (TE), a common form of hair loss. Over 180 days, female participants received either a nutrient-rich supplement containing folic acid or an alternative formulation.

Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.

This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Read More
8
Folic acid treatment shows promise
We explored the effects of folic acid on hair loss in a three-week-old Charolais calf showing signs typical of folic acid deficiency. After starting daily folic acid therapy at a dose of 1 mg/kg, we observed that the crusts and patches diminished within two weeks. Remarkably, hair growth resumed, and within two months, the calf returned to a normal state. This indicates that folic acid could be an effective treatment for certain types of alopecia related to deficiencies in this essential nutrient.
Read More
We investigated the effects of folate within a well-structured study that examined its role in hair loss treatments. Although part of a marketed oral combination for diffuse hair loss, folate's specific impact was challenging to isolate because it was evaluated alongside other compounds.

Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.

Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Read More
7
Folic acid shows limited protective effects
We explored the effects of folic acid on hair loss in zebrafish larvae after exposure to different concentrations of ethanol. This study revealed how gestational ethanol exposure can harm the development of sensory hair cells. We found that even small amounts of ethanol lead to a significant decrease in hair cell count.

When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.

Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
Read More

User Reviews

USERS' SCORE
Good
Based on 103 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Mood improved
20 people found this helpful
After two months on these supplements, my hair loss stopped within the first month. My overall health improved, especially my mood and sleep quality. I also noticed an enhancement in my skin condition, although that may relate more to my skincare routine.
Read More
9
Overcame hair loss
14 people found this helpful
Folic acid with Biotin helped me during a crisis of hair loss. An integrated approach, perhaps including Merz vitamins, contributed to my success. Many believe only pregnant women need folic acid, but everyone, including men, does. Factors like smoking and poor diet can lead to a common deficiency. Symptoms may include irritability and hair loss. After two weeks, my psycho-emotional state improved, my skin became more even, dryness reduced, and notably, hair loss decreased considerably. My hair did become greasier at the roots, and the scalp was less dry throughout the supplementation period.
Read More
9
Recommended by doctor
6 people found this helpful
My doctor suggested this before pregnancy for fetal health, and I noticed it significantly helped my hair loss. I highly recommend it.
Read More
9
Reduced hair loss
6 people found this helpful
This product is great for pregnant women in the early months. I personally observed that it improves my skin and hair significantly while wonderfully reducing hair loss.
Read More
9
Stopped hair loss
2 people found this helpful
Pairing Now Foods Biotin with this supplement virtually stopped my hair loss. The package includes 250 tablets, taken once daily after breakfast. My overall health improved significantly. Within two weeks, I experienced smoother skin and less hair loss; my scalp became oilier, and it’s less dry now.
Read More

Frequently Asked Questions

9
Hair loss reduced
1 people found this helpful
Folic acid with Biotin was key in overcoming my hair loss. Along with Merz vitamins, I found a comprehensive approach effective. Everyone should consider folic acid, as it’s essential for all, not just pregnant women. Lifestyle factors often lead to a deficiency. The improvement in my overall health began within two weeks, significantly reducing hair loss and improving my scalp condition.
9
Hair loss ceased
Good day. These small yellow tablets are easy to swallow and cause no unpleasant sensations. Coupled with Now Foods Biotin, I nearly completely stopped my hair loss. In just two weeks, my scalp's dryness reduced, and my hair fell out much less. My skin's condition improved, and I experienced no discomfort during use.
9
Mood improved
20 people found this helpful
After two months on these supplements, my hair loss stopped within the first month. My overall health improved, especially my mood and sleep quality. I also noticed an enhancement in my skin condition, although that may relate more to my skincare routine.
9
Improved health
After two months on a daily tablet of folic acid combined with iron and Vitamin C, my active hair loss ceased after the first month. I also felt a noticeable improvement in my health, mood, energy, sleep quality, and reduced stress.
9
Effectively stops
This product has wonderfully halted my hair loss, and my skin looks clearer now. I highly recommend it for anyone experiencing similar issues.
9
Comprehensive benefits
Along with Now Foods Biotin, I almost completely stopped hair loss. I took one tablet daily after meals, and within two weeks, I saw improved skin tone and decreased hair fall. Washing my hair became more frequent due to increased oiliness, but there were no adverse effects.
10
Integrated approach effective
Recently, I mentioned my struggle with hair loss. During that tough time, Biotin along with folic acid proved effective. This integrated approach helped me overcome hair loss. Folic acid is essential for everyone, not just pregnant women. I saw improvements in my mood and the health of my skin and hair. After approximately two weeks, significant changes occurred, and hair loss was reduced considerably.
9
Stopped hair loss
This important supplement stopped my hair loss and improved my health. It’s convenient to take, just one small tablet a day lasts over six months. It’s inexpensive, contains necessary ingredients, and there's no risk of overdose as excess is excreted. Always consult a doctor before starting, but I find it excellent.
9
Overcame hair loss
14 people found this helpful
Folic acid with Biotin helped me during a crisis of hair loss. An integrated approach, perhaps including Merz vitamins, contributed to my success. Many believe only pregnant women need folic acid, but everyone, including men, does. Factors like smoking and poor diet can lead to a common deficiency. Symptoms may include irritability and hair loss. After two weeks, my psycho-emotional state improved, my skin became more even, dryness reduced, and notably, hair loss decreased considerably. My hair did become greasier at the roots, and the scalp was less dry throughout the supplementation period.
We explored the effectiveness of two nutritional supplements for treating telogen effluvium (TE), a common form of hair loss. Over 180 days, female participants received either a nutrient-rich supplement containing folic acid or an alternative formulation.

Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.

This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
We investigated the effects of folate within a well-structured study that examined its role in hair loss treatments. Although part of a marketed oral combination for diffuse hair loss, folate's specific impact was challenging to isolate because it was evaluated alongside other compounds.

Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.

Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
7
Folic acid shows limited protective effects
We explored the effects of folic acid on hair loss in zebrafish larvae after exposure to different concentrations of ethanol. This study revealed how gestational ethanol exposure can harm the development of sensory hair cells. We found that even small amounts of ethanol lead to a significant decrease in hair cell count.

When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.

Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.

References

  1. Sant'Anna Addor FA, Donato LC, Melo CSA. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Clin Cosmet Investig Dermatol. 2018;11:431. doi:10.2147/CCID.S173082
  2. Bouvet A, Baird JD, Basrur PK. Folic acid therapy for alopecia in a Charolais calf. Vet Rec. 1988;123:533.
  3. Riegel K, Hengl T, Krischok S, Schlinzig K, Abts HF. L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes. Clin Cosmet Investig Dermatol. 2020;13:499. doi:10.2147/CCID.S254720
  4. Rah YC, Park S, Koun S, Park HC, Choi J. In vivo assay of the ethanol-induced embryonic hair cell loss and the protective role of the retinoic and folic acid in zebrafish larvae (Danio rerio). Alcohol. 2019;75:113. doi:10.1016/j.alcohol.2018.07.008
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